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1

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

Minokoshi, Yasuhiko, Kim, Young-Bum, Peroni, Odile D., Fryer, Lee G. D., Müller, Corinna, Carling, David, Kahn, Barbara B.

Journal:

Year:

2002

Language:

english

File:

PDF, 201 KB

english, 2002

2

Gamma-Aminobutyric Acid Signaling in Brown Adipose Tissue Promotes Systemic Metabolic Derangement in Obesity

Ikegami, Ryutaro, Shimizu, Ippei, Sato, Takeshi, Yoshida, Yohko, Hayashi, Yuka, Suda, Masayoshi, Katsuumi, Goro, Li, Ji, Wakasugi, Takayuki, Minokoshi, Yasuhiko, Okamoto, Shiki, Hinoi, Eiichi, Nielsen

Journal:

Year:

2018

Language:

english

File:

PDF, 4.68 MB

english, 2018

3

An enzymatic photometric assay for 2-deoxyglucose uptake in insulin-responsive tissues and 3T3-L1 adipocytes

Kumiko Saito, Suni Lee, Tetsuya Shiuchi, Chitoku Toda, Masahiro Kamijo, Kyoko Inagaki-Ohara, Shiki Okamoto, Yasuhiko Minokoshi

Journal:

Analytical Biochemistry

Year:

2011

Language:

english

File:

PDF, 832 KB

english, 2011

4

L-Glutamate and Insulin Enhance Glycogen Synthesis in Cultured Astrocytes from the Rat Brain Through Different Intracellular Mechanisms

Meiko Hamai, Yasuhiko Minokoshi, Takashi Shimazu

Journal:

Journal of Neurochemistry

Year:

1999

Language:

english

File:

PDF, 160 KB

english, 1999

5

Effects of denervation and local 6-hydroxydopamine injection on testicular growth in rats

K. Nagai, S. Murano, Y. Minokoshi, H. Okuda, M. Kinutani

Journal:

Cellular and Molecular Life Sciences

Year:

1982

Language:

english

File:

PDF, 732 KB

english, 1982

6

Metabolic adaptation of mice in a cool environment

Kunitoshi Uchida, Tetsuya Shiuchi, Hitoshi Inada, Yasuhiko Minokoshi, Makoto Tominaga

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2010

Language:

english

File:

PDF, 235 KB

english, 2010

7

Decreased Intake of Sucrose Solutions in Orexin Knockout Mice

Eiko Matsuo, Ayako Mochizuki, Kiyomi Nakayama, Shiro Nakamura, Takashi Yamamoto, Seiji Shioda, Takeshi Sakurai, Masashi Yanagisawa, Tetsuya Shiuchi, Yasuhiko Minokoshi, Tomio Inoue

Journal:

Journal of Molecular Neuroscience

Year:

2011

Language:

english

File:

PDF, 371 KB

english, 2011

8

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

Minokoshi, Yasuhiko, Alquier, Thierry, Furukawa, Noboru, Kim, Young-Bum, Lee, Anna, Xue, Bingzhong, Mu, James, Foufelle, Fabienne, Ferré, Pascal, Birnbaum, Morris J.

Journal:

Year:

2004

Language:

english

File:

PDF, 477 KB

english, 2004

9

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

Yamauchi, T., Kamon, J., Minokoshi, Y., Ito, Y., Waki, H., Uchida, S., Yamashita, S., Noda, M., Kita, S., Ueki, K.

Journal:

Nature Medicine

Year:

2002

Language:

english

File:

PDF, 476 KB

english, 2002

10

Role of hypothalamic AMP-kinase in food intake regulation

Yasuhiko Minokoshi, Tetsuya Shiuchi, Suni Lee, Atsushi Suzuki, Shiki Okamoto

Journal:

Year:

2008

Language:

english

File:

PDF, 230 KB

english, 2008

11

Recurrent neonatal seizures: relationship of pathology to the electroencephalogram and cognition

Ivan de Rogalski Landrot, Mitsuko Minokoshi, Diosely C. Silveira, Byung Ho Cha, Gregory L. Holmes

Journal:

Developmental Brain Research

Year:

2001

Language:

english

File:

PDF, 5.97 MB

english, 2001

12

Accelerated norepinephrine turnover in peripheral tissues after ventromedial hypothalamic stimulation in rats

Masayuki Saito, Yasuhiko Minokoshi, Takashi Shimazu

Journal:

Year:

1989

Language:

english

File:

PDF, 473 KB

english, 1989

13

Regulatory mechanism of the ventromedial hypothalamus in enhancing glucose uptake in skeletal muscles

Yasuhiko Minokoshi, Yoshiharu Okano, Takashi Shimazu

Journal:

Year:

1994

Language:

english

File:

PDF, 432 KB

english, 1994

14

Hypothalamic regulation of energy metabolism: Lessons from leptin-AMPK system

Yasuhiko Minokoshi

Journal:

Autonomic Neuroscience

Year:

2007

Language:

english

File:

PDF, 60 KB

english, 2007

15

Orexins increase glucose uptake in skeletal muscle via the hypothalamus-sympathetic nervous system-β2-adrenergic pathway

Tetsuya Shiuchi, Shiki Okamoto, Atsushi Suzuki, Suni Lee, Chitoku Toda, Kumiko Saito, Yasuhiko Minokoshi

Journal:

Autonomic Neuroscience

Year:

2007

Language:

english

File:

PDF, 59 KB

english, 2007

16

Ghrelin raises [Ca2+]i via AMPK in hypothalamic arcuate nucleus NPY neurons

Daisuke Kohno, Hideyuki Sone, Yasuhiko Minokoshi, Toshihiko Yada

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 250 KB

english, 2008

17

Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes

Kazuhisa Maeda, Haiming Cao, Keita Kono, Cem Z. Gorgun, Masato Furuhashi, Kadir T. Uysal, Qiong Cao, Genichi Atsumi, Harry Malone, Bala Krishnan, Yasuhiko Minokoshi, Barbara B. Kahn, Rex A. Parker, Gö

Journal:

Cell Metabolism

Year:

2005

Language:

english

File:

PDF, 729 KB

english, 2005

18

Central Melanocortin Signaling Restores Skeletal Muscle AMP-Activated Protein Kinase Phosphorylation in Mice Fed a High-Fat Diet

Tomohiro Tanaka, Hiroaki Masuzaki, Shintaro Yasue, Ken Ebihara, Tetsuya Shiuchi, Takako Ishii, Naoki Arai, Masakazu Hirata, Hiroshi Yamamoto, Tatsuya Hayashi, Kiminori Hosoda, Yasuhiko Minokoshi, Kazu

Journal:

Cell Metabolism

Year:

2007

Language:

english

File:

PDF, 770 KB

english, 2007

19

Paraventricular hypothalamic AMPK regulates macronutrient selection of carbohydrate and fat diets

Shiki Okamoto, Yasuhiko Minokoshi

Journal:

Neuroscience Research

Year:

2009

Language:

english

File:

PDF, 68 KB

english, 2009

20

Induction of Hypothalamic Sirt1 Leads to Cessation of Feeding via AgRP

Tsutomu Sasaki, Hye-jin Kim, Masaki Kobayashi, Yukari-Ido Kitamura, Hiromi Yokota-Hashimoto, Tetsuya Shiuchi, Yasuhiko Minokoshi, Tadahiro Kitamura

Journal:

Neuroscience Research

Year:

2010

Language:

english

File:

PDF, 55 KB

english, 2010

21

Selective ablation of histamine H1 receptor-expressing neurons in the paraventricular nucleus of the hypothalamus to study their role in the regulation of food intake

Shuhei Horio, Shuji Kitaike, Tetsuya Shiuchi, Yasuhiko Minokoshi, Makoto Sanbo, Takahiro Hirabayashi, Takeshi Yagi, Nobuyuki Kai, Kazuto Kobayashi, Takashi Ueyama, Hiroyuki Fukui

Journal:

Neuroscience Research

Year:

2011

Language:

english

File:

PDF, 105 KB

english, 2011

22

Aggravation of chemically-induced injury in perfused rat liver by extracellular ATP

Tai-Xing Cui, Masaru Iwai, Meiko Hamai, Yasuhiko Minokoshi, Takashi Shimazu, Masatsugu Horiuchi

Journal:

Year:

2000

Language:

english

File:

PDF, 627 KB

english, 2000

23

Microinjection of leptin into the ventromedial hypothalamus increases glucose uptake in peripheral tissues in rats

Yasuhiko Minokoshi, Mohammad Shahidul Haque, Takashi Shimazu

Journal:

Neuroscience Research

Year:

1998

Language:

english

File:

PDF, 120 KB

english, 1998

24

PTP1B Regulates Leptin Signal Transduction In Vivo

Janice M. Zabolotny, Kendra K. Bence-Hanulec, Alain Stricker-Krongrad, Fawaz Haj, Yongping Wang, Yasuhiko Minokoshi, Young-Bum Kim, Joel K. Elmquist, Louis A. Tartaglia, Barbara B. Kahn, Benjamin G. N

Journal:

Developmental Cell

Year:

2002

Language:

english

File:

PDF, 513 KB

english, 2002

25

Alpha-synuclein elicits glucose uptake and utilization in adipocytes through the Gab1/PI3K/Akt transduction pathway

Rodriguez-Araujo, Gerardo, Nakagami, Hironori, Hayashi, Hiroki, Mori, Masaki, Shiuchi, Tetsuya, Minokoshi, Yasuhiko, Nakaoka, Yoshikazu, Takami, Yoichi, Komuro, Issei, Morishita, Ryuichi, Kaneda, Yasu

Journal:

Cellular and Molecular Life Sciences

Year:

2013

Language:

english

File:

PDF, 635 KB

english, 2013

26

Ventromedial hypothalamic stimulation accelerates norepinephrine turnover in brown adipose tissue of rats

Masayuki Saito, Yasuhiko Minokoshi, Takashi Shimazu

Journal:

Year:

1987

Language:

english

File:

PDF, 266 KB

english, 1987

27

Metabolic and morphological alterations of brown adipose tissue after sympathetic denervation in rats

Yasuhiko Minokoshi, Masayuki Saito, Takashi Shimazu

Journal:

Journal of the Autonomic Nervous System

Year:

1986

Language:

english

File:

PDF, 582 KB

english, 1986

28

Enhancement of leptin receptor signaling by SOCS3 deficiency induces development of gastric tumors in mice

Inagaki-Ohara, K, Mayuzumi, H, Kato, S, Minokoshi, Y, Otsubo, T, Kawamura, Y I, Dohi, T, Matsuzaki, G, Yoshimura, A

Journal:

Year:

2014

Language:

english

File:

PDF, 3.87 MB

english, 2014

29

Leptin, GABA, and Glucose Control

Kahn, Barbara B., Minokoshi, Yasuhiko

Journal:

Cell Metabolism

Year:

2013

Language:

english

File:

PDF, 566 KB

english, 2013

30

Role of ventromedial hypothalamus on leptin-induced glucose uptake in peripheral tissues

Toda, Chitoku, Shiuchi, Tetsuya, Minokoshi, Yasuhiko

Journal:

Neuroscience Research

Year:

2009

Language:

english

File:

PDF, 100 KB

english, 2009

31

Role of the hypothalamus in insulin-independent glucose uptake in peripheral tissues

Shimazu, Takashi, Sudo, Makoto, Minokoshi, Yasuhiko, Takahashi, Akira

Journal:

Brain Research Bulletin

Year:

1991

Language:

english

File:

PDF, 512 KB

english, 1991

32

Adrenergic blockade paradoxically increases lipogenic response of brown adipose tissue to sympathetic nerve stimulation

Minokoshi, Yasuhiko, Saito, Masayuki, Shimazu, Takashi

Journal:

Neuroscience Letters

Year:

1990

Language:

english

File:

PDF, 327 KB

english, 1990

33

Central nervous system regulation of glucose uptake in peripheral tissues

Shimazu, Takashi, Minokoshi, Yasuhiko

Journal:

Neuroscience Research Supplements

Year:

1992

Language:

english

File:

PDF, 144 KB

english, 1992

34

Purification of brain-derived lipogenic factor from bovine brain

Minokoshi, Y., Shimazu, T.

Journal:

Pathophysiology

Year:

1994

Language:

english

File:

PDF, 83 KB

english, 1994

35

Purification and characterization of a novel lipogenic factor from bovine brain

Minokoshi, Yasuhiko, Shimazu, Takashi

Journal:

Neuroscience Research Supplements

Year:

1994

Language:

english

File:

PDF, 121 KB

english, 1994

36

906 Regulatory mechanism of the ventromedial hypothalamus in enhancing glucose uptake in skeletal muscles of rats

Minokoshi, Yasuhiko, Shimazu, Takashi

Journal:

Neuroscience Research Supplements

Year:

1993

Language:

english

File:

PDF, 87 KB

english, 1993

37

Lack of TRPM2 Impaired Insulin Secretion and Glucose Metabolisms in Mice

Uchida, K., Dezaki, K., Damdindorj, B., Inada, H., Shiuchi, T., Mori, Y., Yada, T., Minokoshi, Y., Tominaga, M.

Journal:

Year:

2011

Language:

english

File:

PDF, 409 KB

english, 2011

38

Regulation of Pancreatic Cell Mass by Neuronal Signals from the Liver

Imai, J., Katagiri, H., Yamada, T., Ishigaki, Y., Suzuki, T., Kudo, H., Uno, K., Hasegawa, Y., Gao, J., Kaneko, K., Ishihara, H., Niijima, A., Nakazato, M., Asano, T., Minokoshi, Y., Oka, Y.

Journal:

Year:

2008

Language:

english

File:

PDF, 1.03 MB

english, 2008

39

Conditional Ablation of Orexin/Hypocretin Neurons: A New Mouse Model for the Study of Narcolepsy and Orexin System Function

Tabuchi, S., Tsunematsu, T., Black, S. W., Tominaga, M., Maruyama, M., Takagi, K., Minokoshi, Y., Sakurai, T., Kilduff, T. S., Yamanaka, A.

Journal:

Journal of Neuroscience

Year:

2014

Language:

english

File:

PDF, 5.82 MB

english, 2014

40

Microinjection of leptin into the ventromedial hypothalamus increases glucose uptake in peripheral tissues in rats

Minokoshi, Y., Haque, M. S., Shimazu, T.

Journal:

Year:

1999

Language:

english

File:

PDF, 303 KB

english, 1999

41

Extracellular Signal-Regulated Kinase in the Ventromedial Hypothalamus Mediates Leptin-Induced Glucose Uptake in Red-Type Skeletal Muscle

Toda, C., Shiuchi, T., Kageyama, H., Okamoto, S., Coutinho, E. A., Sato, T., Okamatsu-Ogura, Y., Yokota, S., Takagi, K., Tang, L., Saito, K., Shioda, S., Minokoshi, Y.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.29 MB

english, 2013

42

Dmbx1 is essential in agouti-related protein action

Fujimoto, W., Shiuchi, T., Miki, T., Minokoshi, Y., Takahashi, Y., Takeuchi, A., Kimura, K., Saito, M., Iwanaga, T., Seino, S.

Journal:

Proceedings of the National Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 577 KB

english, 2007

43

Muscle-Specific Deletion of the Glut4 Glucose Transporter Alters Multiple Regulatory Steps in Glycogen Metabolism

Kim, Y.-B., Peroni, O. D., Aschenbach, W. G., Minokoshi, Y., Kotani, K., Zisman, A., Kahn, C. R., Goodyear, L. J., Kahn, B. B.

Journal:

Molecular and Cellular Biology

Year:

2005

Language:

english

File:

PDF, 332 KB

english, 2005

44

Disruption of CXC Motif Chemokine Ligand-14 in Mice Ameliorates Obesity-induced Insulin Resistance

Nara, N., Nakayama, Y., Okamoto, S., Tamura, H., Kiyono, M., Muraoka, M., Tanaka, K., Taya, C., Shitara, H., Ishii, R., Yonekawa, H., Minokoshi, Y., Hara, T.

Journal:

Journal of Biological Chemistry

Year:

2007

Language:

english

File:

PDF, 565 KB

english, 2007

45

Leptin Stimulates Fatty Acid Oxidation and Peroxisome Proliferator-Activated Receptor Gene Expression in Mouse C2C12 Myoblasts by Changing the Subcellular Localization of the 2 Form of AMP-Activated Protein Kinase

Suzuki, A., Okamoto, S., Lee, S., Saito, K., Shiuchi, T., Minokoshi, Y.

Journal:

Molecular and Cellular Biology

Year:

2007

Language:

english

File:

PDF, 931 KB

english, 2007

46

Skeletal Muscle AMP-Activated Protein Kinase Phosphorylation Parallels Metabolic Phenotype in Leptin Transgenic Mice Under Dietary Modification

Tanaka, T., Hidaka, S., Masuzaki, H., Yasue, S., Minokoshi, Y., Ebihara, K., Chusho, H., Ogawa, Y., Toyoda, T., Sato, K., Miyanaga, F., Fujimoto, M., Tomita, T., Kusakabe, T., Kobayashi, N., Tanioka,

Journal:

Year:

2005

Language:

english

File:

PDF, 632 KB

english, 2005

47

Role of the sympathetic nervous system and insulin in enhancing glucose uptake in peripheral tissues after intrahypothalamic injection of leptin in rats

Haque, M. S., Minokoshi, Y., Hamai, M., Iwai, M., Horiuchi, M., Shimazu, T.

Journal:

Year:

1999

Language:

english

File:

PDF, 449 KB

english, 1999

48

Tissue-specific Ablation of the GLUT4 Glucose Transporter or the Insulin Receptor Challenges Assumptions about Insulin Action and Glucose Homeostasis

Minokoshi, Y., Kahn, C. R., Kahn, B. B.

Journal:

Journal of Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 644 KB

english, 2003

49

Neuronal Protein Tyrosine Phosphatase 1B Deficiency Results in Inhibition of Hypothalamic AMPK and Isoform-Specific Activation of AMPK in Peripheral Tissues

Xue, B., Pulinilkunnil, T., Murano, I., Bence, K. K., He, H., Minokoshi, Y., Asakura, K., Lee, A., Haj, F., Furukawa, N., Catalano, K. J., Delibegovic, M., Balschi, J. A., Cinti, S., Neel, B. G., Kahn

Journal:

Molecular and Cellular Biology

Year:

2009

Language:

english

File:

PDF, 2.65 MB

english, 2009

50

Distinct Effects of Leptin and a Melanocortin Receptor Agonist Injected Into Medial Hypothalamic Nuclei on Glucose Uptake in Peripheral Tissues

Toda, C., Shiuchi, T., Lee, S., Yamato-Esaki, M., Fujino, Y., Suzuki, A., Okamoto, S., Minokoshi, Y.

Journal:

Year:

2009

Language:

english

File:

PDF, 245 KB

english, 2009